Next-Generation Biomaterials: Engineering Responsive Hydrogels for Targeted Drug Delivery in Chronic Wounds

Abstract

Chronic wounds present notable clinical difficulties because of their slow healing process and susceptibility to infections. This research focuses on developing advanced biomaterials, especially responsive hydrogels designed for precise drug delivery to aid wound healing. These hydrogels feature stimuli-responsive mechanisms that regulate the release of therapeutic agents in response to the wound environment, such as changes in pH, enzyme activity, and temperature. By integrating biocompatible polymers with improved drug encapsulation techniques, these hydrogels demonstrate better adhesion, increased mechanical strength, and consistent drug release.